Probably by now, you may have read some articles about CBD and THC. But I’m pretty sure there are still questions lingering on in your mind.

Is there really a difference between CBD and THC? If so, how would that affect me as a user? Which should I choose?

This article will help clear out all your confusion once and for all. You will also learn about the effects of both CBD and THC.

What You Need to Know About Cannabidiol

Cannabidiol or CBD is one of the beneficial substances you can find in the cannabis Sativa plant family. You can find CBD in both industrial hemp and marijuana.

CBD gained its popularity because of its benefits, mainly as a pain reliever. Its most significant medical contribution is its help in combatting certain epileptic conditions.

This chemical compound does not contain psychoactive properties. So, if you are expecting to get high, you’ve got the wrong substance.

The Power of Tetrahydrocannabinol

On the other hand, tetrahydrocannabinol (THC) is the most prevalent substance in marijuana. Industrial hemp also contains THC, but only in small concentrations.

How does it actually give the kick? Well, let me start by discussing ECS.

You and Your Endocannabinoid System

According to the National Institutes of Health, ECS is a group of lipids and the receptors attached to them. They can be found all over our body.

Two cannabinoid receptors are found on our ECS: CB1 receptor and CB2 receptor. CB1 receptors can mostly be found in the brain, while CB2 receptors are mainly in the immune cells.

Now, back to THC. Once THC gets inside your body, it binds with your CB1 receptor, thus, giving the psychoactive effect. Unlike THC, CBD does not bind to any of the receptors.

Both compounds have the same atomic makeup. CBD and THC have 30 hydrogen atoms, 21 carbon atoms, and 2 oxygen atoms.

They both affect our neurotransmitters. However, they were arranged uniquely; that’s why they give different side effects.

Now, let’s continue the bout.

Medical Benefits

Both compounds almost have the same medical benefits. However, they don’t have the same side effects.

Check out the conditions both CBD and THC could help you with:

Mental DisorderX
Inflammatory Bowel DiseaseX
Low AppetiteX
Muscle SpasticityX

You may want to check your condition with a medical provider before considering which is the better option.

Side Effects

CBD does not have known adverse side effects to date. Though overdosage may cause nausea and vomiting, it is still not fatal.

However, you must remember that any medication combination might have varying effects. So, if you are taking other medicines, you may not want to take CBD.

Other than the psychoactive effect, THC may cause:

  • Red eyes
  • Slower motion
  • Loss of memory
  • Dry mouth
  • Hand and eye coordination
  • Heart rate increase

Don’t fret because these effects are temporary. THC is also not fatal but it may have long-lasting psychiatric effect when consumed in large doses.

Some studies found that teenagers who overuse THC are prone to have schizophrenia and other mental conditions. Moderate intake is severely advised.

Legal Status

When it comes to legality, CBD has more advantage than THC for now. Thanks to Farm Bill 2018, producers can now grow industrial hemp as long as it contains zero to 0.03% THC.

But that does not mean CBD is already off the hook. Some states in the U.S. still consider CBD as a marijuana compound. Marijuana is illegal; therefore, CBD is still illegal.

If you plan to go on a trip to get CBD, you may want to avoid South Dakota, Idaho, and Nebraska. Be careful because the neighboring states may be friendly but these three are still strict about it.

Even with the federal mandate, it may take a while for these states to enjoy the benefits of CBD. Some authorities still confiscate CBD products.

Meanwhile, THC is still not legal because marijuana is still considered an illegal substance. Some states may have approved the use of marijuana but at a controlled amount.

Chemical Structure

As I have mentioned, CBD and THC have different chemical makeup: the sadoesme atoms, different arrangements. Here’s how they look like:


The C21H30O2 makeup of both substances is arranged uniquely. It is also the reason CBD do not bind with the CB1 receptor, unlike THC.

If ever CBD binds with the receptor, it may be too weak that it would let go. On the other hand, once THC holds on to the receptor, it gives the euphoric sensation.

Here’s Your Takeaway

Both CBD and THC are beneficial to your body. In fact, when you combine both, they become one of the most powerful natural medicine ever discovered.

This entourage effect even compliments each substance. Studies showed that CBD somehow helps control the psychoactive effect of THC and instead give relief.

Yes, entourage effect sounds like you and your pop girlfriends waving at your fans while you walk the red carpet. Get this: there is an ongoing study that the CBD and THC combo can help fight cancer complications.


Knowing the difference between CBD and THC would help you with your buying decision. Definitely, you would opt for something that would address your needs. That’s the key there: identify your needs before buying.

The society may still be conservative about it, most especially when they hear the words “hemp” or “marijuana.” You can’t be a superhero and discuss these matters to everyone who sees you using CBD or THC.

And even when you are given the chance, some people would still feel icky about it. This is just like what happened to the Farm Bill. Even when it’s already federal law, some states are still against it.

Consequently, change is inevitable. There will come a time that everyone would agree on your buying decisions now. But you don’t have to wait for it to happen.

You are the master of your fate. It is still up to you to know what’s best for yourself. At the end of it all, your health matters.